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High level extracellular production of recombinant human interferon alpha 2b in glycoengineered Pichia pastoris: culture medium optimization,high cell density cultivation and biological characterization |
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| Authors: | S. Katla B. Karmakar S.R.R. Tadi N. Mohan B. Anand U. Pal S. Sivaprakasam |
| Affiliation: | 1. BioPAT Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India;2. MAB Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India;3. Molecular Endocrinology Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India |
| Abstract: | |
| Keywords: | artificial neural network design of experiments genetic algorithm growth kinetics interferon alpha 2b Pichia pastoris |