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In vitro potentiation of carbapenems with tannic acid against carbapenemase-producing enterobacteriaceae: exploring natural products as potential carbapenemase inhibitors
Authors:A.M. Somboro  J. Osei Sekyere  D.G. Amoako  H.M. Kumalo  R. Khan  L.A. Bester  S.Y. Essack
Affiliation:1. Antimicrobial Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Biomedical Resource Unit, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa;2. Department of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa;3. Antimicrobial Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa;4. Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban, South Africa;5. Biomedical Resource Unit, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa

Abstract:
Keywords:carbapenem  carbapenemase  efflux pump  efflux pump inhibitors  Enterobacteriaceae  enzymatic inhibition assay  MBL inhibitors  Tannic acid
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