Expression of estrogen receptor alpha and beta during mouse embryogenesis. |
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| Authors: | J G Lemmen J L Broekhof G G Kuiper J A Gustafsson P T van der Saag B van der Burg |
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| Affiliation: | Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands. |
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| Abstract: | In adult mammals numerous target tissues and organs for estrogens exist. Little is known about possible target organs during embryogenesis other than the reproductive tract and the gonads. This is the first report on the expression of estrogen receptor beta (ERbeta) in comparison with ERalpha mRNA during mouse embryogenesis. We found expression of estrogen receptor mRNA in the reproductive tract, but also in the atrial wall, brain, kidney, urethra, bladder neck, mammary gland primordium, midgut, cartilage primordia and perichondria. |
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