| 植物核小RNA研究进展 |
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| 引用本文： | 胡亮,程捷,王义华,吕孟薇,宋剑波.植物核小RNA研究进展[J].生物化学与生物物理进展,2021,48(5):505-514. |
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| 作者姓名： | 胡亮 程捷 王义华 吕孟薇 宋剑波 |
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| 作者单位： | 1）江西农业大学生物科学与工程学院,南昌 330045,1）江西农业大学生物科学与工程学院,南昌 330045,2）江西农业大学理学院,南昌 330045,3）江西农业大学国土资源与环境学院,南昌 330045,1）江西农业大学生物科学与工程学院,南昌 330045 |
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| 基金项目： | 江西省教育厅科学基金（GJJ170276） |
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| 摘 要： | 核小RNA (small nuclear RNA,snRA)是一类长度为60～300 nt的非编码RNA,是真核生物RNA剪接体的主要成分. snRNA在各种生物中具有较高的保守性和同源性,主要参与了mRNA和rRNA前体的加工过程.本文对当前植物中snRNA领域的研究成果进行简要概述,介绍了植物snRNA的分类、基因结构、合成机制及生物学功能,同时总结了植物snRNA的化学修饰以及在科研生产中的应用,并对将来snRNA的研究方向进行了展望.
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| 关 键 词： | 植物snRNA 剪接体 修饰 基因调控 |
| 收稿时间： | 2020/7/31 0:00:00 |
| 修稿时间： | 2020/10/12 0:00:00 |
Advances in Plant Small Nuclear RNA Research |
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| Institution: | 1)College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang 330045, China,1)College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang 330045, China,2)College of Science, Jiangxi Agricultural University, Nanchang 330045, China,3)College of Land Resources and Environment, Jiangxi Agricultural University, Nanchang 330045, China,1)College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang 330045, China |
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| Abstract: | snRNA (small nuclear RNA) is a type of non-coding RNA with a length of 60 to 300 nt. Among the 15 known snRNAs, U1, U2, U4, U5, and U6 are the main components of eukaryotic RNA spliceosomes. The structure of snRNA is relatively conservative, with a cap structure and sm/Lsm structure at the 5'' end, and a stem-loop structure at the 3'' end. The main function of snRNA is to splice pre-mRNA and rRNA to produce corresponding mature mRNA and other non-coding RNA. In plants, snRNA can also participate in plant physiology and growth regulation. In recent years, it has been discovered that snRNA ends contain many modifications, including methylation, uridylation and adenylylation, etc. These modifications have an important impact on the processing and degradation of snRNA. Here, this paper briefly summarizes the current research results in the field of snRNA, including classification, gene structure, synthesis mechanism and biological function in plants. In addition, it also introduces the chemical modification of plant snRNA and its application in scientific research, and looks forward to the future research direction of snRNA. |
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| Keywords: | plant snRNA spliceosome modification gene regulation |
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