| 化脓性链球菌磷酸酶转移系统研究进展 |
| |
| 引用本文： | 宋英莉,陈竑量,王胜钰,蔡明辉,朱辉. 化脓性链球菌磷酸酶转移系统研究进展[J]. 微生物学杂志, 2021, 0(2): 101-107 |
| |
| 作者姓名： | 宋英莉 陈竑量 王胜钰 蔡明辉 朱辉 |
| |
| 作者单位： | 哈尔滨医科大学 生理学教研室，黑龙江 哈尔滨 150081 |
| |
| 基金项目： | 国家自然科学基金项目（81571957）；黑龙江省大学生创新创业训练计划项目（201910226031）；黑龙江省政府博士后基金项目（LBH-Z19175） |
| |
| 摘 要： | 化脓性链球菌(Streptococcus pyogenes)是一种引起人类多种疾病的革兰阳性病原菌,其磷酸烯醇丙酮酸依赖性磷酸转移酶系统(Phosphoenol pyruvate-dependent phosphotransferase pathway,PTS)由系统通透酶(EII)、通用PTS系统蛋白酶I(EI)和含...
|
| 关 键 词： | 细菌磷酸酶转移系统 化脓性链球菌 糖摄取 毒力 碳代谢 |
Advances in Phosphatase Transfer System of Streptococcus pyogenes |
| |
| SONG Ying-li,CHEN Hong-liang,WANG Sheng-yu,CAI Ming-hui,ZHU Hui. Advances in Phosphatase Transfer System of Streptococcus pyogenes[J]. Journal of Microbiology, 2021, 0(2): 101-107 |
| |
| Authors: | SONG Ying-li CHEN Hong-liang WANG Sheng-yu CAI Ming-hui ZHU Hui |
| |
| Affiliation: | Teach & Res. Div. of Physiol., Harbin Med. Uni., Harbin 150081 |
| |
| Abstract: | Streptococcus pyogenes is a gram-positive pathogen that causes many human diseases. Its phosphoenol pyruvate-dependent phospho-transferase pathway (PTS) is composed of system permease (EII), general PTS, system protease I (EI), and histidine-containing protein (HPr) regulated by the phosphorylation state of HPr, and has functions of ingesting glucose, sugar, and fructose. The PTS component affects the expression of SLS, Mga and sagA and other virulent factors. This article mainly reviews the components of the PTS system, its regulatory mechanism, carbohydrate intake, and its effects on virulence, and provides a basis for in-depth research on regulatory network and metabolic pathways affected by the Streptococcus pyogenes PTS system. |
| |
| Keywords: | bacterial phosphatase transfer system Streptococcus pyogenes sugar intake virulence carbon metabolism |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《微生物学杂志》浏览原始摘要信息 |
|
点击此处可从《微生物学杂志》下载全文 |
|
