D-aspartic acid in purified myelin and myelin basic protein |
| |
| Authors: | G H Fisher N M Garcia I L Payan R Cadilla-Perezrios W A Sheremata E H Man |
| |
| Affiliation: | 1. Department of Chemistry, University of Miami, Coral Gables, FL 33124 USA;2. Department of Neurology, University of Miami School of Medicine Miami, FL 33101 USA |
| |
| Abstract: | The presence of the biologically uncommon D-isomer of aspartic acid in the white matter of human brains has been reported previously from this laboratory (1). We now report that the level of D-aspartate in human brains is higher in purified myelin than in white matter and is even higher in the myelin basic protein fraction. There also appears to be a difference in the level of D-aspartate found in human brain as compared to bovine brain, possibly a species or age-related difference. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
