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PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1
Authors:Wang Shuai  Wang Huibo  Davis Ben C  Liang Jiyong  Cui Rutao  Chen Sai-Juan  Xu Zhi-Xiang
Institution:aState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;bDivision of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35205, USA;cDepartment of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA;dDepartment of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
Abstract:
Keywords:PARP1 inhibitor  AKT  FOXO3A  PHLPP1
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