Crystallographic study of the anti-tumor protein ricin |
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Authors: | J E Villafranca J D Robertus |
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Institution: | Clayton Foundation Biochemical Institute Department of Chemistry University of Texas Austin, Texas 78712 U.S.A. |
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Abstract: | The anti-tumor protein ricin (also called RCAII) has been crystallized in a form suitable for X-ray diffraction analysis. The crystal symmetry is orthorhombic spacegroup P212121 with and a single ricin molecule of molecular weight 65,000 per asymmetric unit. The crystals diffract well and are stable in the X-ray beam. At least one useful heavymetal derivative has been found as part of a high-resolution study. |
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