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E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide |
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| Authors: | Su Hyoun Lee Yun Ju Lee Sungyeon Jung Kwang Chul Chung |
| Affiliation: | Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea |
| Abstract: | |
| Keywords: | Parkinson’ s disease, FBXO7, SIRT7, ubiquitin E3 ligase, aging, proteasome degradation, hydrogen peroxide |