Permeability of Frog Skeletal Muscle Cells to Choline

Using choline-methyl-C¹⁴ as a tracer, it has been shown that choline⁺ penetrates into the cells of resting frog skeletal muscle at a rate similar to that of Na⁺, and that it escapes from these cells much more slowly than does Na⁺. Some implications of these findings are discussed.