Oleanane-type triterpenes from the flowers, pith, leaves, and fruit of Tetrapanax papyriferus |
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| Authors: | Ho Jiau-Ching Chen Chiu-Ming Row Lie-Ching |
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| Institution: | Department of Chemical and Materials Engineering, Ta Hwa Institute of Technology, Chung-Lin, Hsinchu, 307 Taiwan, ROC. |
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| Abstract: | Four oleanane-type triterpenes, 3alpha,21beta,22alpha-trihydroxy-11,13(18)-oleanadien-28-oic acid (1), 3-epi-papyriogenin C (2), 21-O-acetyl-21-hydroxy-3-oxo-11,13(18)-oleanadien-28-oic acid (3) and 3beta-hydroxy-21-oxo-11,13(18)-oleanadien-28-oic acid methyl ester (4), together with four known triterpenes, were isolated from Tetrapanax papyriferus (Hook) K. Koch. Papyriogenin A (8) exhibited anti-HIV activity and low cytotoxicity in acutely infected H9 lymphocytes. Their structures were determined by analysis of spectroscopic data, including by 1D and 2D NMR. |
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| Keywords: | Tetrapanax papyriferus Araliaceae Oleanane-type triterpene |
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