Influence of maternal adrenalectomy on the ultrastructure of the adrenal gland in neonatal rats |
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| Authors: | Peter A. Nickerson Mirjana Hristić Prof. Dr. Vladimir Pantić |
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| Affiliation: | (1) Department of Pathology, SUNY — Buffalo and Institute for Biological Research, Belgrade, Yugoslavia;(2) Institute for Biological Research, The University of Belgrade, 29. Novembra, 142 Belgrad, Yugoslavia |
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| Abstract: | Maternal adrenalectomy at 7 or 14 days of gestation produced increased cell necrosis within zona reticularis cells on the day of birth and at 24 or 48 h after birth. Small remnants or large portions of adrenocortical cells were present within macrophages. In otherwise normal adrenocortical cells, lipid droplets were incorporated within some mitochondria. Autophagocytosis of single mitochondria was observed within adrenocortical cells. Undoubtedly ultrastructural changes represent stimulation of adrenocortical cells in neonatal rats in response to maternal adrenalectomy. |
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| Keywords: | Maternal adrenalectomy Rat Influence on the adrenals of newborn animals Electron microscopy |
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