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Common precursors of human blood group MN specificities
Authors:G F Springer  P R Desai
Institution:Department of Immunochemistry Research, Evanston Hospital, and the Department of Microbiology, Northwestern University, Evanston, Illinois 60201, USA
Abstract:Human blood group MM and NN specific structures have the same precursors. Complete sialic acid removal produced the Thomsen-Friedenreich T antigen which was transformed into Tn antigen by E. coli β-D-galactosidase on red cells as well as on isolated T antigen. MN antigens and their precursors are most clearly defined by isologous human antisera.
Keywords:NANA  N-acetylneuraminic acid  Gal  GalNAc  Glc  GlcNAc  Man  Mannose  OSM  Ovine submaxillary mucin  RDE
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