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Effect of medium composition on L-Lysine production by a variant strain ofCorynebacterium clutamicum ATCC 21513
Authors:A Hadj Sassi  N Coello  A M Deschamps  J M Lebeault
Institution:(1) Division des Procénés Biotechnologiques, Université de Technologie de Compiègne, BP 233-60206, Compiegne, (France);(2) Present address: Laboratoire de Microbiologie Alimentaire et de Biotechnologie-Université de Bordeaux I, 33405 Talence Cedex, France
Abstract:Summary The strainCorunebacterium glutamicum ATCC 21513 grown in a medium containing 17.5% glucose, 5.5% ammonium sulphate and 2% yeast extract was found to produce (under laboratory conditions) high amounts of L-Lysine in this optimized medium. Lysine production, residual sugar and dry cell mass were measured as a function of fermentation time. It was observed that l g of cell mass produced 2.96 g of Lysine. The conversion efficiency was found to be 44%.
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