Proposal for a scoring of the quality of the banding of chromosomes |
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| Authors: | J. L. Huret C. Leonard A. Aurias |
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| Affiliation: | (1) Laboratoire Cytogénétique Hématologique, CHU La Milétrie, F-86021 Poitiers Cedex, France;(2) Laboratoire Histo-Embryo-Cytogénétique, CHU Bicetre, 78, rue du Général Leclerc, F-94270 Kremlin-Bicêtre Cedex, France;(3) UA 620 CNRS, Institut Curie, 26, rue d'Ulm, F-75231 Paris Cedex 05, France |
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| Abstract: | Summary We propose an objective scoring of the quality of the banding of mitoses based on the number of bands (B), the length (L), and the width (W) of chromosome 7 in metaphase as used in the formula ![$$left. {left[ {LnBsqrt {frac{L}{W}} } right.} right]^2$$](/content/g462242161224u06/439_2004_Article_BF00284111_TeX2GIFIE1.gif) . When no figure shows the quality of mitoses from which a breakpoint is described, this scoring could give information about it. It could be applied in cytogenetic cancer studies as well as for preparations with high resolution banding. |
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