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Synthesis and hybridization properties of oligonucleotides containing 6-membered azasugar nucleotides
Authors:Jung K E  Kim K  Yang M  Lee K  Lim H
Affiliation:

AgroPharma Research Institute, Dongbu Research Council, 103-2 Yusung-Gu, Moonji-Dong, Taejon, Korea 305-380

Abstract:A modified nucleoside was synthesized with adenine and a 6-membered azasugar, and it was converted to the phosphoramidite which was used for the incorporation into oligonucleotides. The hybridization properties of the modified oligonucleotides with DNA and RNA were studied.
Keywords:
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