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Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli
Authors:Hilal Taymaz‐Nikerel  Marjan De Mey  Gino J E Baart  Jo Maertens  Maria Remedios Foulquié‐Moreno  Daniel Charlier  Joseph J Heijnen  Walter M van Gulik
Institution:1. +90 212 3597457+90 212 2872460;2. Department of Biotechnology, Delft University of Technology, Kluyver Centre for Genomics of Industrial Fermentation, Julianalaan 67, 2628 BC Delft, The Netherlands;3. Present address: Department of Chemical Engineering, Bogazici University, 34342 Bebek, Istanbul, Turkey;4. Department of Biochemical and Microbial Technology, Centre of Expertise‐Industrial Biotechnology and Biocatalysis, Ghent University, Ghent, Belgium;5. Department of Applied Mathematics, Biometrics and Process Control, Ghent University, Ghent, Belgium;6. Present address: Leuven Institute for Beer Research, CMPG Lab for Genetics and Genomics, University of Leuven, Leuven, Belgium;7. Department of Applied Biological Sciences, Research Group of Microbiology, Vrije Universiteit Brussel, Brussels, Belgium;8. Present address: Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Flanders, Belgium;9. Present address: Department of Molecular Microbiology, VIB, Kasteelpark Arenberg 31, Flanders, Belgium
Abstract:
Keywords:succinate  Escherichia coli  metabolomics  metabolic flux analysis  chemostat culture  dynamic changes
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