Thalamic stimulation effects on reactive depression |
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| Authors: | O J Andy F Jurko |
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| Institution: | Department of Neurosurgery, University of Mississippi Medical Center, Jackson. |
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| Abstract: | Depression was evaluated in 10 patients before and after therapeutic mesothalamic brain stimulation for chronic pain. Minnesota multiphasic personality inventory T scores for depression were high in all patients before stimulation. Scores were decreased in 8 of 10 patients with chronic deep brain stimulation, three of whom returned to normal. Pain relief was good to excellent in 9 of 10 patients. It is concluded that depression is secondary to pain or pain-inducing factors which implicate the catecholamine and serotonergic systems. |
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