Chemical constituents from Mentha canadensis |
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| Affiliation: | 1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China;2. Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;3. Center of Scientific Experiment, Beijing University of Chinese Medicine, Beijing 100029, China;1. Research and Innovation Centre, Fondazione Edmund Mach (FEM), Via E. Mach 1, 38010 San Michele all''Adige, TN, Italy;2. TerraData environmetrics, via L. Bardelloni 19, 58025 Monterotondo M.mo, Grosseto, Italy;1. Department of Agronomy, SAPVESA Laboratory, Nature and Life Sciences Faculty, University Chadli Bendjedid El-Tarf, 36000, Algeria;2. Department of Biochemistry, Biochemistry and Environmental Toxicology Laboratory, University Badji Mokhtar Annaba, 23000, Algeria;3. Department of Biology, Laboratory of Plant Biotechnology, National Institute of Applied Science and Technology (INSAT), BP. 676, 1080 Tunis Cedex, Tunisia;4. Department of Natural and Life Sciences, Laboratory of Ecotoxicology and Abiotic Stress, University of Constantine 1, 25000 Constantine, Algeria |
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| Abstract: | Phytochemical investigation on Mentha canadensis led to the isolation of two new compounds, 3,4-dihydro-3,6,7-trihydroxy-2(1H)-quinolinone (1), (E)-2-methoxy-2- oxethyl-3-(4-hydroxyphenyl) acrylate (2), along with nine known phenolic compounds, syringic acid (3), p-coumaric acid (4), esculetin (5), methyl rosmarinate (6), nepetoidin B (7), syringaresinol (8), methyl ester of caffeoyl glycollic acid (9), 2″,3″-diacetylmartynoside (10) and bracteanolide A (12). Additionally, cis-3-[2-[1-(3,4-dihydroxyphenyl)-1-hydroxymethyl]-1,3-benzodioxol-5-yl]-(E)-2-propenoic acid (11), which was isolated as a natural product for the first time. All these compounds were reported for the first time from this species, and their structures were elucidated by spectroscopic techniques. Compound 11 may be a useful chemotaxonomic marker for M. canadensis. The p-coumaric acid derivatives identified in the present investigation may have chemotaxonomic significance at the generic level. |
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| Keywords: | Lamiaceae |
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