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Enhancement of the Stability of Insoluble Calcium Particles Using a Phospholipid Coating
Authors:Naiyan Lu  Xuan Zhang  Jiaoyang Song  Xuejian Yu  Joe M Regenstein  Peng Zhou
Institution:1.State Key Laboratory of Food Science and Technology,Jiangnan University,Jiangsu Province,People’s Republic of China;2.Department of Food Science,Cornell University,Ithaca,USA
Abstract:Calcium is one of the most important elements in the human body. Insoluble calcium particles are often used in calcium-fortified food products, such as calcium-fortified milk, dairy beverages or protein powders. However, their suspension may be unstable often leading to precipitation in such products. In this study, three different kinds of insoluble calcium particles, i.e. hydroxyapatite (HA), tricalcium phosphate (TCP) and calcium carbonate (CaCO3) were coated with amphiphilic phospholipids using a solvent-exchange method. Suspension stability of these insoluble calcium particles was effectively improved with phospholipid coating, especially for HA and TCP, as more phospholipids were coated on the surface of these two calcium particles than CaCO3. Phospholipid coating increased the electrostatic repulsions between particles, preventing the particles from aggregating and precipitating. In addition, the digestibility of phospholipid-coated insoluble calcium particles was tested in simulated gastric juice, and the dissolution time of these insoluble calcium particles was prolonged through phospholipid coating.
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