Detection of estrogen receptors ER-alpha and ER-beta in human ejaculated immature spermatozoa with excess residual cytoplasm |
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Authors: | Vittoria Rago Laura Siciliano Saveria Aquila Amalia Carpino |
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Affiliation: | (1) Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy;(2) Department of Pharmaco-Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy |
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Abstract: | Background A key role of estrogens in human sperm biology has been recently suggested by aromatase and estrogen receptor detection in human testicular germ cells and ejaculated spermatozoa. However, the involvement of these hormones in the sperm maturation process is still not defined. The aim of this work was to investigate the expression of estrogen receptors, ER-alpha and ER-beta, in human ejaculated immature spermatozoa with excess residual cytoplasm. |
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