Reduced Context Effects on Retrieval in First-Episode Schizophrenia |
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| Authors: | Lucia M. Talamini Lieuwe de Haan Dorien H. Nieman Don H. Linszen Martijn Meeter |
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| Affiliation: | 1. Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.; 2. Academic Medical Center, Department of Psychiatry, University of Amsterdam, Amsterdam, The Netherlands.; 3. Department of Cognitive Psychology, VU University, Amsterdam, The Netherlands.;Chiba University Center for Forensic Mental Health, Japan |
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| Abstract: | BackgroundA recent modeling study by the authors predicted that contextual information is poorly integrated into episodic representations in schizophrenia, and that this is a main cause of the retrieval deficits seen in schizophrenia.Methodology/Principal FindingsWe have tested this prediction in patients with first-episode schizophrenia and matched controls. The benefit from contextual cues in retrieval was strongly reduced in patients. On the other hand, retrieval based on item cues was spared.Conclusions/SignificanceThese results suggest that reduced integration of context information into episodic representations is a core deficit in schizophrenia and one of the main causes of episodic memory impairment. |
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