ACTIVATION OF PIG BRAIN GLUTAMINASE |
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Authors: | Gerd Svenneby |
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Affiliation: | Department of Neurochemistry, The University Psychiatric Clinic, Vinderen, Oslo 3, Norway |
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Abstract: | Pig brain glutaminase (EC 3.5.1.2, l -glutamine amidohydrolase) is activated by certain anions (e.g. phosphate, fluoride, carboxylic acids) and inhibited by others (e.g. chloride, bromide, iodide and glutamate). The only cation which has been found to activate the enzyme is the ammonium ion. This applies to both the tris-HCl form and the phosphate-borate form of glutaminase. |
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