Stimulation of resistance to Taenia taeniaeformis in the rat by infection with Fasciola hepatica |
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| Authors: | N J Campbell J D Kelly I C Martin |
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| Affiliation: | 1. New South Wales Department of Agriculture, Veterinary Research Station, Glenfield, N.S.W. 2167, Australia;2. Department of Veterinary Pathology, University of Sydney, Sydney, N.S.W. 2006, Australia;3. Department of Veterinary Physiology, University of Sydney, Sydney, N.S.W. 2006, Australia |
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| Abstract: | Homologous resistance to F. hepatica and T. taeniaeformis and cross resistance between these two parasites was investigated in the rat. Rats given a primary infection with F. hepatica were challenged with either F. hepatica or T. taeniaeformis. Conversely rats given a primary infection with T. taeniaeformis were challenged with either F. hepatica or T. taeniaeformis.Infection with F. hepatica generated significant resistance against challenge with F. hepatica given 9 weeks later. Similarly, infection with T. taeniaeformis protected against challenge with T. taeniaeformis given 6 weeks later. Infection with F. hepatica also generated significant resistance against challenge with T. taeniaeformis given 4, 8 or 9 weeks later. Primary infection with T. taeniaeformis did not protect against challenge with F. hepatica. |
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| Keywords: | Taenia taeniaeformis homologous resistance cross resistance |
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