The age distribution of cells in stratified squamous epithelium |
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Authors: | David R. Appleton Nicholas A. Wright Paul Dyson |
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Affiliation: | Departments of Medical Statistics and Pathology, University of Newcastle upon Tyne, England |
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Abstract: | In structured tissues such as stratified squamous epithelium the age distribution of cycling cells in a particular part of the tissue is influenced by cell migration. Age distributions are derived for the proliferative cells of stratified squamous epithelium, dependent on the mode of migration; and the effect of using analytical methods which assume exponential or rectangular age distributions is discussed with particular reference to the analysis of stathmokinetic experiments. |
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