Familial neurofibromatosis and juvenile chronic myelogenous leukemia |
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Authors: | Robin D. Clark John J. Hutter Jr. |
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Affiliation: | (1) Department of Pediatrics, University of Arizona Health Sciences Center, 85724 Tuscon, Arizona, USA;(2) Present address: Genetics Division, Harbor General Hospital, Torrance, California, USA |
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Abstract: | Summary Two male children with familial neurofibromatosis were observed to develop juvenile chronic myelogenous leukemia. These two cases add to previous reports which have described an increased incidence of non-lymphocytic leukemia in patients with neurofibromatosis. In particular, the rare entity juvenile chronic myelogenous leukemia would appear to be the form of non-lymphocytic leukemia that has a definite association with familial neurofibromatosis. |
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