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Familial neurofibromatosis and juvenile chronic myelogenous leukemia
Authors:Robin D. Clark  John J. Hutter Jr.
Affiliation:(1) Department of Pediatrics, University of Arizona Health Sciences Center, 85724 Tuscon, Arizona, USA;(2) Present address: Genetics Division, Harbor General Hospital, Torrance, California, USA
Abstract:Summary Two male children with familial neurofibromatosis were observed to develop juvenile chronic myelogenous leukemia. These two cases add to previous reports which have described an increased incidence of non-lymphocytic leukemia in patients with neurofibromatosis. In particular, the rare entity juvenile chronic myelogenous leukemia would appear to be the form of non-lymphocytic leukemia that has a definite association with familial neurofibromatosis.
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