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NRF2 deficiency reduces life span of mice administered thoracic irradiation
Authors:Travis Elizabeth L  Rachakonda Girish  Zhou Xinhui  Korhonen Katrina  Sekhar Konjeti R  Biswas Swati  Freeman Michael L
Affiliation:
  • a Department of Experimental Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
  • b Department of Radiation Oncology, Vanderbilt University School of Medicine and the Vanderbilt-Ingram Cancer Center, Nashville, TN 37232, USA
  • Abstract:
    Keywords:Radiation-induced fibrosis   Late normal tissue injury   NRF2   TGF-β   Nrf2 null mice   PAI-1   FSP-1   Free radicals
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