Complete Sequence of the First Chimera Genome Constructed by Cloning the Whole Genome of Synechocystis Strain PCC6803 into the Bacillus subtilis 168 Genome |
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| Authors: | Satoru Watanabe Yuh Shiwa Mitsuhiro Itaya Hirofumi Yoshikawa |
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| Affiliation: | aDepartment of Bioscience;bGenome Research Center, Tokyo University of Agriculture, Tokyo, Japan;cLaboratory of Genome Designing Biology, Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan |
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| Abstract: | Genome synthesis of existing or designed genomes is made feasible by the first successful cloning of a cyanobacterium, Synechocystis PCC6803, in Gram-positive, endospore-forming Bacillus subtilis. Whole-genome sequence analysis of the isolate and parental B. subtilis strains provides clues for identifying single nucleotide polymorphisms (SNPs) in the 2 complete bacterial genomes in one cell. |
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