Production,purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1 |
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| Authors: | Guillaume G Nicolas Gisèle LaPointe Marc C Lavoie |
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| Institution: | 1.Département de Biochimie Microbiologie et Bioinformatique, Faculté des Sciences et Génie,Université Laval,Québec (Québec),Canada;2.Centre de Recherche en Sciences et Technologie du Lait (STELA), Institut des Nutraceutiques et des Aliments Fonctionnels (INAF), Faculté des Sciences de l'Agriculture et de l'Alimentation,Université Laval,Québec (Québec),Canada;3.Département de Stomatologie, Faculté de Médecine Dentaire,Université de Montréal,Montréal (Québec),Canada;4.Department of Biological and Chemical Sciences, Faculty of Pure and Applied Sciences,The University of the West Indies,Bridgetown,Barbados |
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| Abstract: | Background The increase in bacterial resistance to antibiotics impels the development of new anti-bacterial substances. Mutacins (bacteriocins)
are small antibacterial peptides produced by Streptococcus mutans showing activity against bacterial pathogens. The objective of the study was to produce and characterise additional mutacins
in order to find new useful antibacterial substances. |
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