Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related species |
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| Authors: | Oliver Keller Florian Odronitz Mario Stanke Martin Kollmar Stephan Waack |
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| Institution: | 1.Universit?t G?ttingen,Institut für Informatik,G?ttingen,Germany;2.Max-Planck-Institut für Biophysikalische Chemie,Abteilung NMR-basierte Strukturbiologie,G?ttingen,Germany;3.Universit?t G?ttingen, Institut für Mikrobiologie und Genetik,Abteilung Bioinformatik,G?ttingen,Germany |
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| Abstract: | Background For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although
a vast amount of genomic sequence data is available, precise annotation of genes is lacking behind. Finding the corresponding
gene of a given protein sequence by means of conventional tools is error prone, and cannot be completed without manual inspection,
which is time consuming and requires considerable experience. |
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