Adjuvant arthritis in Lewis and AVN inbred strain of rats.

The authors analysed the manifestations of adjuvant arthritis in inbred Lewis and AVN rats and in subsequent generations (F1, F2, B1, B2), using a subjective (scoring system) and an objective criterion (paw volume). The results obtained were in good correlation. Marked variability of the systemic symptoms of the disease was found not only in the parent generation but also in the subsequent generations.