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Two populations of somatostatin-immunoreactive neurons in the guinea pig striatum |
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| Authors: | Steven R Vincent Marcus von Krosigk |
| Institution: | (1) Division of Neurological Sciences, Department of Psychiatry, The University of British Columbia, Vancouver, British Columbia, Canada;(2) Division of Neurological Sciences, Department of Psychiatry, The University of British Columbia, V6T 1W5 Vancouver, B.C., Canada;(3) Present address: MRC Anatomical Neuropharmacology Unit, University Department of Pharmacology, South Parks Road, OXI 3QT Oxford, UK |
| Abstract: | Summary Two populations of neurons displaying somatostatin-like immunoreactivity were detected immunohistochemically in the guinea pig striatum using a monoclonal antibody. Sparse, well-stained neurons similar to those described in other species were observed throughout the guinea pig caudate-putamen. These neurons contained both neuropeptide Y and NADPH-diaphorase in addition to somatostatin. A second large population of somatostatin immunoreactive neurons in which these other substances did not coexist was found within the putamen. |
| Keywords: | Somatostatin (SRIF) Striatum Neuropeptides Caudate-putamen Immunohistochemistry Guinea pig |
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