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PCR Detection of Type I Polyketide Synthase Genes in Myxobacteria |
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| Authors: | Hisayuki Komaki Ryosuke Fudou Takashi Iizuka Daisuke Nakajima Koei Okazaki Daisuke Shibata Makoto Ojika Shigeaki Harayama |
| Abstract: | The diversity of type I modular polyketide synthase (PKS) was explored by PCR amplification of DNA encoding ketosynthase and acyltransferase domains in myxobacteria. The sequencing of the amplicons revealed that many PKS genes were distantly related to the published sequences. Thus, myxobacteria may be excellent resources for novel and diverse polyketides. |
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