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The lipoprotein lipase-encoding human gene: sequence from intron-6 to intron-9 and presence in intron-7 of a 40-million-year-old Alu sequence. |
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| Authors: | Jean-Claude Chuat Alain Raisonnier Jacqueline Etienne Francis Galibert |
| Affiliation: | a Laboratoire d'Hématologie Expérimentale, Centre Hayem, Hôpital St-Louis, Paris, France Tel. (33-1) 42 02 1605 b Laboratoire de Biochimie, Faculté de Médecine St-Antoine, Paris, France |
| Abstract: | The complete nucleotide sequence of the 3877-bp segment spanning the 3′ region of intron-6 to the 5′ region of intron-9 of the human lipoprotein lipase (LPL)-encoding ten-exon gene, LPL, is reported. An Alu repeat present in intron-7 was found by sequence analysis to belong to the 40–55-million-year-old Alu-Se subclass. |
| Keywords: | Recombinant DNA nucleotide sequencing triglycerides fatty acids illegitimate recombination phylogeny exons pathology hyperchylomicronemia |
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