Polynucleotides. V. Titration and spectrophotometric studies upon the interaction of synthetic polynucleotides with various dyes |
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| Authors: | STEINER R F BEERS R F |
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| Affiliation: | 1. DSM Ahead R&D BV, Advanced Chemical Engineering Solutions (ACES), P.O. Box 18, 6160 MD Geleen, The Netherlands;2. Laboratory of Physical Chemistry, Department of Chemical Engineering and Chemistry & Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands;1. Department of Geography, Haldia Government College, Haldia, West Bengal, India;2. Department of Geography, PRMS Mahavidyalaya, West Bengal, India;3. Department of Geography, Bankura University, Bankura, West Bengal, India;1. Laboratory of Physical Chemistry, Department of Chemical Engineering and Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands;2. DSM Ahead R&D BV, Advanced Chemical Engineering Solutions (ACES), Urmonderbaan 22, 6160 MD Geleen, The Netherlands |
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| Abstract: | The dyes acridine orange and methylene blue have been found to undergo a striking change in visible and ultraviolet absorption spectra in the presence of polyriboadenylic acid and polyribocytidylic acid. This reaction does not occur with the corresponding monomers. In the case of polyriboadenylic acid, the binding of acridine orange appears to inhibit the structural change of this polymer at acid pH's. |
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