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Meliternatin: a feeding deterrent and larvicidal polyoxygenated flavone from Melicope subunifoliolata
Authors:Hung Ho Shuit  Wang Jing  Sim K Y  Ee Gwendoline C L  Imiyabir Zamrie  Yap K F  Shaari Khozirah  Hock Goh Swee
Affiliation:Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. dbshosh@nus.edu.sg
Abstract:We screened more than 60 Malaysian plants against two species of insects and found that Melicope subunifoliolata (Stapf) T.G. Hartley (Rutaceae) showed strong feeding deterrent activity against Sitophilus zeamais Motsch. (Curculionidae) and very good larvicidal activity against Aedes aegypti L. (Diptera). One anti-insect compound, meliternatin (3,5-dimethoxy-3',4',6,7-bismethylendioxyflavone) (6) and six other minor polyoxygenated flavones were isolated from M. subunifoliolata.
Keywords:Melicope subunifoliolata   Rutaceae   Feeding deterrence   Larvicidal activity   Sitophilus zeamais   Aedes aegypti   Flavonoid   Meliternatin
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