A new translocation t(1;4;11) in congenital acute nonlymphocytic leukemia (acute myeloblastic leukemia) |
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| Authors: | A Selypes A László |
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| Institution: | (1) Department of Hygiene and Epidemiology, University Medical School, Dóm tér, 10, H-6720 Szeged, Hungary;(2) Department of Pediatrics, University Medical School, Korányi fasor 14-15, H-6720 Szeged, Hungary |
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| Abstract: | Summary A new translocation t(1;11;4)(1pter 1p32::11q23 11q13::4p164qter) was found in the peripheral blood of a patient with congenital acute myeloblastic leukemia (AML). It was concluted that this translocation may represent a new mutation, which caused the leukemia with very high leukocytosis, hepatosplenomegaly, leukemic infiltration of the majority of the organs, and a very poor prognosis. |
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