Next-Generation Sequencing in the Mycology Lab |
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Authors: | Jan Zoll Eveline Snelders Paul E Verweij Willem J G Melchers |
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Institution: | 1.Department of Medical Microbiology,Radboud University Medical Centre,Nijmegen,The Netherlands;2.Institut Pasteur,Unité de Mycologie Moléculaire,Paris,France |
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Abstract: | New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for sequence analysis provides a potential powerful tool in mycological diagnosis and research. In this review, we summarize the applications of next-generation sequencing techniques in mycology. |
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