Antifungal Penetration into the Nail and New Topicals for Onychomycosis |
| |
Authors: | Lindsey M Childs-Kean Jacqueline Jourjy |
| |
Institution: | 1.Department of Pharmacotherapy and Translational Research,University of Florida College of Pharmacy,Seminole,USA;2.Department of Pharmacotherapy and Translational Research,University of Florida College of Pharmacy,Orlando,USA |
| |
Abstract: | Onychomycosis is a common and difficult to treat infection, owing predominately to the limited penetration of topical drugs to the site of infection. Systemic drugs are not an option for all patients due to adverse events and drug-drug interactions. In this article, we review the nail penetration and clinical efficacy data of topical drugs, including older agents such as ciclopirox and amorolfine, as well as the newer agents, efinaconazole and tavaborole. Additionally, we describe some unresolved questions in the management of onychomycosis. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|