MutS2 Family Protein from Pyrococcus furiosus |
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Authors: | Ravi Vijayvargia Indranil Biswas |
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Affiliation: | (1) National Centre for Cell Science, Pune University Campus, Ganeshkhind, Pune 411007, India, IN |
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Abstract: | MutS2 protein of Pyrococcus furiosus has been cloned and over-expressed. Initial characterization reveals that PfuMutS2 possesses a thermostable ATPase activity and a thermostable, nonspecific DNA binding activity. However, PfuMutS2 does not have any detectable mismatch-specific DNA binding activity. It is the first in vitro characterization of an MutS2 family protein. Received: 23 April 2001 / Accepted: 27 August 2001 |
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