Further constituents from Caralluma negevensis |
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Authors: | Bader Ammar Braca Alessandra De Tommasi Nunziatina Morelli Ivano |
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Institution: | Faculty of Pharmacy, Al-Zaytoonah University of Jordan, PO Box 130, 11733 Amman, Jordan. |
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Abstract: | Two new megastigmane glycosides (1 and 2) and two new flavone glycosides (3 and 4) were isolated from the methanol extract of the whole plant of Caralluma negevensis Zohary (Asclepiadaceae). The structures of the isolated compounds were characterized as (9R)-2beta,9-dihydroxymegastigma-4,7-dien-3-one-9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (1), 2beta,9-dihydroxymegastigma-4-en-3-one 9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (2), luteolin 3'-O-beta-D-glucopyranoside-4'-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside (3), and luteolin 3',4'-di-O-beta-D-glucopyranoside (4). The structures of the isolated compounds were established on the basis of spectral evidence and chemical transformation. |
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Keywords: | Caralluma negevensis Asclepiadaceae Megastigmane glycosides Flavone glycosides |
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