Metabolism during anaesthesia and recovery in colic and healthy horses: a microdialysis study |
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Authors: | Anna H Edner Birgitta Essén-Gustavsson Görel C Nyman |
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Affiliation: | (1) Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden;(2) Department of Medical Sciences, Clinical Physiology, University hospital, Uppsala, Sweden |
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Abstract: | Background Muscle metabolism in horses has been studied mainly by analysis of substances in blood or plasma and muscle biopsy specimens. By using microdialysis, real-time monitoring of the metabolic events in local tissue with a minimum of trauma is possible. There is limited information about muscle metabolism in the early recovery period after anaesthesia in horses and especially in the colic horse. The aims were to evaluate the microdialysis technique as a complement to plasma analysis and to study the concentration changes in lactate, pyruvate, glucose, glycerol, and urea during anaesthesia and in the recovery period in colic horses undergoing abdominal surgery and in healthy horses not subjected to surgery. |
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