| 弥散加权成像联合磁共振波谱分析在脑梗死中的应用研究 |
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| 引用本文： | 李伟,龙晚生,罗学毛,陈曼琼,兰勇,胡茂清.弥散加权成像联合磁共振波谱分析在脑梗死中的应用研究[J].上海生物医学工程,2011(3):155-161. |
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| 作者姓名： | 李伟 龙晚生 罗学毛 陈曼琼 兰勇 胡茂清 |
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| 作者单位： | 广东省江门市中心医院放射科; |
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| 基金项目： | 江门市科技攻关项目(江科2010[73]-1) |
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| 摘 要： | 目的探讨脑梗死弥散加权成像（DWI）和磁共振波谱分析（MRS）的特点和影响因素,及二者对评估脑梗死的临床价值。方法采用Philips Achieva 1.5T双梯度超导磁共振扫描仪,对72例临床疑是脑梗死患者行常规T1WI、T2WI、FLAIR、DWI、MRS检查,在工作站上测定梗死核心区、内缘区、外缘区、周围区和镜像区的ADC值和代谢物Lac、NAA、Cr、Cho、NAA/Cr、Lac/Cr、Lac/NAA值。结果 DWI显示的梗死灶范围较常规MRI像更加准确、清晰;超急性期、急性期、亚急性期和慢性期梗死核心区的Lac/Cr值和Lac/NAA值高于对侧镜像区,ADC值和NAA/Cr值低于对侧镜像区,存在统计学差异（P〈0.05）;DWI的影响因素有b值、扩散系数、T2穿透效应和各向异性等,MRS的影响因素有磁场均匀性、压水压脂性能、体素、TE与TR、组织代谢物浓度和波谱采集链等。结论 DWI结合MRS能更加全面地评估缺血半暗带,更精确地对脑梗死进行分期和定位。
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| 关 键 词： | 弥散加权成像 磁共振波谱分析 脑梗死 代谢物 |
The Applied Research of Diffusion Weighted Imaging Combined with Magnetic Resonance Spectroscopy in Cerebral Infarction |
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| Li Wei,Long Wansheng,Luo Xuemao,Chen Manqiong,Lan Yong,Hu Maoqing.The Applied Research of Diffusion Weighted Imaging Combined with Magnetic Resonance Spectroscopy in Cerebral Infarction[J].Shanghai Journal of Biomedical Engineering,2011(3):155-161. |
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| Authors: | Li Wei Long Wansheng Luo Xuemao Chen Manqiong Lan Yong Hu Maoqing |
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| Institution: | Li Wei,Long Wansheng,Luo Xuemao,Chen Manqiong,Lan Yong,Hu Maoqing(Department of Radiology,Jiangmen Central Hospital,Jiangmen 529030,China) |
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| Abstract: | Objective Study the characteristics and influencing factors of diffusion weighted imaging and magnetic resonance spectroscopy in cerebral infarction,and the clinical value of them on the assessment of cerebral infarction.Methods By use Philips Achieva 1.5T dual gradient superconducting magnetic resonance scanner,72 patients with suspected cerebral infarction were underwent routine T1WI,T2WI,FLAIR,DWI,MRS examination,at the workstation,measure the ADC values and metabolite values,such as Lac,NAA,Cr,Cho,NAA/C... |
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| Keywords: | diffusion weighted imaging magnetic resonance spctroscopy cerebral infarction metabolite |
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