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Mass transfer analysis for immobilized cells of Lactococcus lactis sp. using both simulations and in-situ pH measurements |
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| Authors: | Cachon Remy Lacroix Christophe Divies Charles |
| Affiliation: | (1) Laboratoire de Microbiologie U.A. INRA, ENSBANA, Université de Bourgogne, 1-esplanade Erasme, 21000 Dijon, France;(2) Centre de Recherche Stela, Faculte des Sciences de l'Agriculture et de l'Alimentation, Universite Laval, Sainte-Foy, Quebec, Canada, G1K 7P4 |
| Abstract: | Mathematical modeling and in-situ pH measurements were used to characterize the effects of the microenvironment on alginate gel beads immobilized cells of Lactococcus lactis. Mass transfer limitations led to a progressive pH acidification within gel beads which determined both the cell distribution and the cellular activity of entrapped cells. The dynamics of the system is discussed in relation to the overall activity of the immobilized cell reactor. |
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