Proteome analysis of resting human neutrophils |
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| Authors: | de Souza Castro Mariana de Sá Natan Monsores Gadelha Renata Pedroza de Sousa Marcelo Valle Ricart Carlos André Ornela Fontes Belchor Fontes Wagner |
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| Institution: | Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil. |
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| Abstract: | Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis-mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural. |
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