Two phosphorylation reactions induced by murine beta interferon in BALB/c-3T3 cells. |
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| Authors: | S Tominaga |
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| Affiliation: | Department of Biochemistry II, Jichi Medical School, Tochigi, Japan. |
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| Abstract: | Treatment with 1000 units/ml of murine beta-interferon enhanced an adenylate kinaselike activity and markedly increased the level of L-alpha-phosphatidyl inositol 4-monophosphate in quiescent BALB/c-3T3 cells. The addition of platelet-derived growth factor (22 units/ml) or poly(I).poly(C) (0.3-1 microgram/ml) to the phosphorylation reaction mixture did not alter this interferon action. |
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