Some common properties of lectins from marine algae |
| |
Authors: | Hori Kanji Miyazawa Keisuke Ito Keiji |
| |
Affiliation: | (1) Faculty of Applied Biological Science, Hiroshima University, 724 Higashi-Hiroshima, Japan |
| |
Abstract: | Twelve kinds of lectins isolated from four species of marine algae, Boodlea coacta (Chlorophyta) and Hypnea japonica, Carpopeltis flabellata and Solieria robusta (Rhodophyta), were compared for their chemical and biological properties. These lectins were proteins or glycoproteins, similar to terrestrial plant lectins. However, unlike most terrestrial plant lectins, they had a small molecular size (4,200 to 25,000 daltons), were mostly monomeric, and had no affinity for monosaccharides. They strongly agglutinated trypsin-treated rabbit erythrocytes, and their activities commonly were inhibited by glycoproteins bearing N-glycans. From hemagglutination-inhibition tests with various glycoproteins and related compounds, it was found that B. coacta lectins recognize high-mannose N-glycans; H. japonica lectins complex N-glycans, and C. flabellata and S. robusta lectins recognize both types of N-glycans. |
| |
Keywords: | agglutinins chemical property lectins seaweeds sugar-binding specificity |
本文献已被 SpringerLink 等数据库收录! |
|