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L-海因酶与D-海因酶的序列及结构比较研究
引用本文:许伟,严明,许琳.L-海因酶与D-海因酶的序列及结构比较研究[J].生物加工过程,2004,2(4):17-21.
作者姓名:许伟  严明  许琳
作者单位:1. 南京工业大学,制药与生命科学学院,南京,210009;盐城工学院,化学工程系,盐城,224003
2. 南京工业大学,制药与生命科学学院,南京,210009
基金项目:国家 973项目 (项目编号 2 0 0 3CB7160 0 0 )
摘    要:运用生物信息学的研究方法,从序列及结构上对L型及D型海因酶进行了初步的比较。研究了两种类型的海因酶在序列、骨架结构及活性中心的区别,并探讨了产生这些差异的理论基础,为海因酶进一步的理论及应用研究提供一定的指导。

关 键 词:L-海因酶  D-海因酶  序列  结构
文章编号:1672-3678(2004)04-0017-05
修稿时间:2004年9月30日

Comparative study of sequences and structures from L-hydantoinase and D-hydantoinase
XU Wei ,YAN Ming ,XU Lin.Comparative study of sequences and structures from L-hydantoinase and D-hydantoinase[J].Chinese Journal of Bioprocess Engineering,2004,2(4):17-21.
Authors:XU Wei    YAN Ming  XU Lin
Institution:XU Wei 1,2,YAN Ming 1,XU Lin 1
Abstract:Hydantoinase is a key enzyme in the production of pure optical amino acids It plays a very important role in some aspects such as pharmaceutical,food industry In this paper bioinformatics methods were used to study the differences of sequences and structures between L hydantoinase and D hydantoinase The differences between two types of hydantoinase were concluded through comparison of their sequences, structures and active sites This paper will provide theory basis for further research on the hydantoinases
Keywords:L  hydantoinase  D  hydantoinase  sequence  structure
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