Genomic comparison between a virulent type A1 strain of Francisella tularensis and its attenuated O-antigen mutant |
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Authors: | Modise Thero Ryder Cheryl Mane Shrinivasrao P Bandara Aloka B Jensen Roderick V Inzana Thomas J |
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Affiliation: | Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA. |
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Abstract: | We report the complete genome sequences of TI0902, a highly virulent type A1 strain, and TIGB03, a related, attenuated chemical mutant strain. Compared to the wild type, the mutant strain had 45 point mutations and a 75.9-kb duplicated region that had not been previously observed in Francisella species. |
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