<Emphasis Type="Italic">Clavispora lusitaniae</Emphasis> and <Emphasis Type="Italic">Chaetomium atrobrunneum</Emphasis> as Rare Agents of Cutaneous Infection |
| |
Authors: | Hao Zhang Yuping Ran Dongming Li Yongfang Liu Yun Xiang Ruifeng Zhang Yaling Dai |
| |
Institution: | (1) Department of Dermatology, Sichuan University West China Hospital, Chengdu, China;(2) Department of Dermatology, Peking University Third Hospital, Beijing, China;(3) Department of Infectious Disease, Affiliated Hospital of North Sichuan Medical College, Nanchong, China |
| |
Abstract: | We describe the first case of cutaneous infection caused by Chaetomium atrobrunneum and Clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid. He presented to our outpatient
center with a 6-day history and previously ineffective antibacterial therapy. Scanning electron microscopy (SEM) revealed
hyphae and spores were on the surface of the crusty exudates and also penetrated into it, and the microbiology study further
showed their characteristic cultural features. Fungal isolates were identified by the amplification and sequencing of the
26S RNA gene and of the ITS region, as C. lusitaniae and C. atrobrunneum. Up until now, most known clinical records of these rare species have shown them as agents of deep mycosis. Due to the emergency
situation, medications were administered promptly and confirmed by subsequent fungal identification and successful therapeutic
outcome. This article illustrates the importance of recognizing fungal infections, especially those caused by uncommon pathogens.
Limitations in the routine identification procedures and therapeutic options of this emerging opportunistic agent are also
discussed in this report. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|